Using a hypothetical example, this blog post explains what is meant by two different types of approach to data analysis in clinical trials: ‘As treated’ (AT) and ‘Intention to treat’ (IT). It also discusses the pros and cons associated with each approach. It concludes that neither approach is inherently better than the other. Rather, the appropriate approach to take will depend on the particular question(s) the analyst is most interested in using the data to answer. For instance, IT may be most appropriate if you’re interested in looking at how different treatments compare in terms of their acceptability to your sample of patients. Alternatively, AT may be most appropriate if you are primarily interested in the difference in effectiveness of the different interventions being compared. Read the blog
Students 4 Best Evidence (S4BE) is a growing network of students from around the world, from school age to university, who are interested in learning more about evidence-based healthcare (EBH). The network is supported by the UK Cochrane Centre. In addition to the website, the S4BE has a Facebook group and Twitter feed. For more information, read Selena Ryan-Vigs blog which introduces Students 4 Best Evidence.