3-3 Are the treatments practical in your setting?

A fair comparison of the effects of a surgical procedure done in a specialised hospital may not provide a reliable estimate of the effects and safety of the same procedure performed in other settings. Similarly, comparing a new drug to a drug or dose that is not commonly used (and which may be less effective or safe than those in common use) would not provide a good estimate of how the new drug compares to what is commonly done.

Be aware that your circumstances may be sufficiently different from those in the research studies, and that the results may not apply to you.

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